Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions
Abstract
Complex numbers: The number of molecules detected in the evanescent field during single-molecule fluorescence imaging decreases with increasing molecular weight in free solution (see graphic; FITC = fluorescein isothiocyanate). This technique could be useful for screening undefined molecular interactions at extremely low concentrations without separation.
Recommended Citation
H. Gai et al., "Correlations between Molecular Numbers and Molecular Masses in an Evanescent Field and their Applications in Probing Molecular Interactions," Angewandte Chemie International Edition, vol. 44, no. 32, pp. 5107 - 5110, Wiley-VCH Verlag Berlin, Aug 2005.
The definitive version is available at https://doi.org/10.1002/ange.200500461
Department(s)
Chemistry
Keywords and Phrases
Evanescent Field; Fluorescence; Molecule Counting; Oligonucleotides; Single-molecule Studies
International Standard Serial Number (ISSN)
1433-7851
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2005 Wiley-VCH Verlag Berlin, All rights reserved.
Publication Date
01 Aug 2005
