Pediatric Ocular Nanomedicines: Challenges and Opportunities

Abstract

The eye is a highly complex, yet readily accessible organ within the human body. As such, the eye is an appealing candidate target for a vast array of drug therapies. Despite advances in ocular drug therapy research, the focus on pediatric ocular drug delivery continues to be highly underrepresented due to the limited number of degenerative ocular diseases with childhood onset. In this review, we explore more deeply the reasons underlying the disparity between ocular therapies available for children and for adults by highlighting diseases that most commonly afflict children (with focus on the anterior eye) and existing prognoses, recent developments in ocular drug delivery systems and nanomedicines for children, and barriers to use for pediatric patients

Department(s)

Chemical and Biochemical Engineering

Keywords and Phrases

Compliance; Drug administration; Nanomedicine; Ocular drug delivery; Pediatric

International Standard Serial Number (ISSN)

1001-8417

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2017 The Authors, All rights reserved.

Publication Date

01 Sep 2017

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