Dendrimers for Ocular Drug Delivery
Abstract
Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this minireview, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.
Recommended Citation
M. G. Lancina and H. Yang, "Dendrimers for Ocular Drug Delivery," Canadian Journal of Chemistry, vol. 95, no. 9, pp. 897 - 902, NRC Research Press, May 2017.
The definitive version is available at https://doi.org/10.1139/cjc-2017-0193
Department(s)
Chemical and Biochemical Engineering
Keywords and Phrases
Dendrimer; Nanomedicine; Ocular drug delivery
International Standard Serial Number (ISSN)
0008-4042; 1480-3291
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2017 Canadian Science Publishing, All rights reserved.
Publication Date
11 May 2017
Comments
This work was supported by the National Institutes of Health (R01EY024072).