Dendrimer-Based RNA Interference Delivery for Cancer Therapy
RNA interference (RNAi) has emerged as a promising tool for cancer treatment. A strenuous ongoing effort for translation of RNAi into clinically acceptable therapy is the development of vectors for efficient and targeted RNAi delivery. In this chapter, we review RNAi-based cancer treatment and the utility of dendrimers in RNAi delivery.
L. Xu et al., "Dendrimer-Based RNA Interference Delivery for Cancer Therapy," ACS Symposium Series, vol. 1135, pp. 197 - 213, American Chemical Society (ACS), Jul 2013.
The definitive version is available at https://doi.org/10.1021/bk-2013-1135.ch012
Chemical and Biochemical Engineering
Keywords and Phrases
Dendrimers; Diseases; Medical applications; RNA, Cancer therapy; RNA interference, Functional polymers
International Standard Book Number (ISBN)
International Standard Serial Number (ISSN)
Article - Journal
© 2013 American Chemical Society (ACS), All rights reserved.
08 Jul 2013