Dendrimer-Based RNA Interference Delivery for Cancer Therapy

Abstract

RNA interference (RNAi) has emerged as a promising tool for cancer treatment. A strenuous ongoing effort for translation of RNAi into clinically acceptable therapy is the development of vectors for efficient and targeted RNAi delivery. In this chapter, we review RNAi-based cancer treatment and the utility of dendrimers in RNAi delivery.

Department(s)

Chemical and Biochemical Engineering

Keywords and Phrases

Dendrimers; Diseases; Medical applications; RNA, Cancer therapy; RNA interference, Functional polymers

International Standard Book Number (ISBN)

978-084122798-9

International Standard Serial Number (ISSN)

0097-6156; 1947-5918

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2013 American Chemical Society (ACS), All rights reserved.

Publication Date

08 Jul 2013

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