Inorganic Nanoparticles for Cancer Imaging and Therapy
Abstract
Inorganic nanoparticles have received increased attention in the recent past as potential diagnostic and therapeutic systems in the field of oncology. Inorganic nanoparticles have demonstrated successes in imaging and treatment of tumors both ex vivo and in vivo, with some promise towards clinical trials. This review primarily discusses progress in applications of inorganic nanoparticles for cancer imaging and treatment, with an emphasis on in vivo studies. Advances in the use of semiconductor fluorescent quantum dots, carbon nanotubes, gold nanoparticles (spheres, shells, rods, cages), iron oxide magnetic nanoparticles and ceramic nanoparticles in tumor targeting, imaging, photothermal therapy and drug delivery applications are discussed. Limitations and toxicity issues associated with inorganic nanoparticles in living organisms are also discussed.
Recommended Citation
H. Huang et al., "Inorganic Nanoparticles for Cancer Imaging and Therapy," Journal of Controlled Release, vol. 155, no. 3, pp. 344 - 357, Elsevier B.V., Nov 2011.
The definitive version is available at https://doi.org/10.1016/j.jconrel.2011.06.004
Department(s)
Chemical and Biochemical Engineering
Keywords and Phrases
Carbon nanotubes; Ceramic nanoparticles; Gold nanoparticles; Magnetic nanoparticles; Quantum dots; Theranostics
International Standard Serial Number (ISSN)
0168-3659
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2011 Elsevier B.V., All rights reserved.
Publication Date
01 Nov 2011
PubMed ID
21723891
