Abstract
There is disclosed a method for the crystallization of benzphetamine hydrochloride from an organic medium by the steps of removing water from the system to a very low level and then reducing the temperature of the organic medium to provide crystallization of the acid salt. In the event that crystallization does not occur upon lowering the temperature of the medium, it has been discovered that gentle heating of the organic medium results in crystallization of the acid salt. It has also been discovered that higher temperature crystallization has been provided by removal of methamphetamine from the composition. The crystalline benzphetamine hydrochloride can then be isolated by typical liquid/solid separation means such as filtration or centrifugation.
Recommended Citation
D. J. Kalota and K. Tomazi, "Crystallization Method for Benzphetamine,", Jul 2010.
Department(s)
Chemical and Biochemical Engineering
Patent Application Number
11/719,001
Patent Number
US007750187B2
Document Type
Patent
Document Version
Final Version
File Type
text
Language(s)
English
Publication Date
July 6, 2010
