Abstract
Molecular imaging has undergone significant development in recent years for its excellent ability to image and quantify biologic processes at cellular and molecular levels. Its application is of significance in cardiovascular diseases, particularly in diagnosing them at early stages. Atherosclerosis is a complex, chronic, and progressive disease that can lead to serious consequences such as heart strokes or infarctions. Attempts have been made to detect atherosclerosis with molecular imaging modalities. Not only do imaging modalities develop rapidly, but research of relevant nanomaterials as imaging probes has also been increasingly studied in recent years. This review focuses on the latest developments in the design and synthesis of probes that can be utilized in computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound imaging, photoacoustic imaging and combined modalities. The challenges and future developments of nanomaterials for molecular imaging modalities are also discussed.
Recommended Citation
H. Kou and H. Yang, "Molecular Imaging Nanoprobes and their Applications in Atherosclerosis Diagnosis," Theranostics, vol. 14, no. 12, pp. 4747 - 4772, Ivyspring International Publisher, Jan 2024.
The definitive version is available at https://doi.org/10.7150/thno.96037
Department(s)
Chemical and Biochemical Engineering
Keywords and Phrases
atherosclerosis; computed tomography; magnetic resonance imaging; molecular imaging; photoacoustic imaging; positron emission tomography; ultrasound imaging
International Standard Serial Number (ISSN)
1838-7640
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2024 The Authors, All rights reserved.
Creative Commons Licensing
This work is licensed under a Creative Commons Attribution 4.0 License.
Publication Date
01 Jan 2024
