Surface Molecularly Imprinted Polymers for the Recognition of Protein
Abstract
A surface molecular imprinting technique used for the production of protein recognitive materials is presented. Functional monomers were photopolymerized on a template mask with immunoglobulin immobilized in a specific molecular orientation. after polymerization, the molecularly imprinted materials were removed from the template mask, yielding a surface with memory for the template immunoglobulin. These materials were then tested for recognition of the desired molecule in a solution containing various competitive biomolecules. It was shown that the materials made with the surface imprinting technique were able to specifically recognize and bind the target molecule while rejecting other competing species. Easy preparation of the surface imprinted polymers, their high stability, and their selectivity toward biomacromoleeules make this technique promising in the application of biological assays and sensors, etc.
Recommended Citation
Y. Zheng and D. B. Henthorn, "Surface Molecularly Imprinted Polymers for the Recognition of Protein," AIChE Annual Meeting, Conference Proceedings, American Institute of Chemical Engineers, Dec 2007.
Department(s)
Chemical and Biochemical Engineering
International Standard Book Number (ISBN)
978-081691022-9
Document Type
Article - Conference proceedings
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 American Institute of Chemical Engineers, All rights reserved.
Publication Date
01 Dec 2007
