Abstract
Bioactive glass particles (0.42SiO2-0.15CaO-0.23Na 2O-0.20ZnO) of varying size (<90 >μm and 425-850 μm) were synthesized and coated with silver (Ag) to produce Ag coated particles (PAg). These were compared against the uncoated analogous particles (Pcon.). Surface area analysis determined that Ag coating of the glass particles resulted in increased the surface area from 2.90 to 9.12 m2/g (90 μm) and 1.09-7.71 m2/g (425-850 μm). Scanning electron microscopy determined that the Ag coating remained at the surface and there was little diffusion through the bulk. Antibacterial (Escherichia coli - 13 mm and Staphylococcus epidermidis - 12 mm) and antifungal testing (Candida albicans - 7.7 mm) determined that small Ag-coated glass particles exhibited the largest inhibition zones compared to uncoated particles. pH analysis determined an overall higher pH consider in the smaller particles, where after 24 h the large uncoated and Ag coated particles were 8.27 and 8.74 respectively, while the smaller uncoated and Ag coated particles attained pH values of 9.63 and 9.35 respectively. © Springer Science+Business Media, LLC 2012.
Recommended Citation
A. W. Wren et al., "Silver Coated Bioactive Glass Particles for Wound Healing Applications," Journal of Materials Science: Materials in Medicine, vol. 23, no. 5, pp. 1331 - 1341, Springer, May 2012.
The definitive version is available at https://doi.org/10.1007/s10856-012-4604-8
Department(s)
Chemical and Biochemical Engineering
International Standard Serial Number (ISSN)
1573-4838; 0957-4530
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2023 The Authors, All rights reserved.
Creative Commons Licensing
This work is licensed under a Creative Commons Attribution 4.0 License.
Publication Date
01 May 2012
PubMed ID
22426653
Included in
Biochemical and Biomolecular Engineering Commons, Biomedical Devices and Instrumentation Commons
