Abstract
Immediate control of uncontrolled bleeding and infection are essential for saving lives in both combat and civilian arenas. Inorganic well-ordered mesoporous silica and bioactive glasses have recently shown great promise for accelerating hemostasis and infection control. However, to date, there has been no comprehensive report assessing their specific mechanism of action in accelerating the hemostasis process and exerting an antibacterial effect. After providing a brief overview of the hemostasis process, this review presents a critical overview of the recently developed inorganic mesoporous silica and bioactive glass-based materials proposed for hemostatic clinical applications and specifically investigates their unique characteristics that render them applicable for hemostatic applications and preventing infections. This article also identifies promising new research directions that should be undertaken to ascertain the effectiveness of these materials for hemostatic applications.
Recommended Citation
S. Pourshahrestani et al., "Well-Ordered Mesoporous Silica and Bioactive Glasses: Promise for Improved Hemostasis," Biomaterials Science, vol. 7, no. 1, pp. 31 - 50, Royal Society of Chemistry, Jan 2019.
The definitive version is available at https://doi.org/10.1039/c8bm01041b
Department(s)
Chemical and Biochemical Engineering
International Standard Serial Number (ISSN)
2047-4849; 2047-4830
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2023 Royal Society of Chemistry, All rights reserved.
Publication Date
01 Jan 2019
PubMed ID
30374499
Included in
Biochemical and Biomolecular Engineering Commons, Biomedical Devices and Instrumentation Commons
Comments
Universiti Malaya, Grant PG077-2015B