Novel Neuropeptides in the Control of Food Intake. Neuronostatin and Nesfatin-1.

Author

Gina L.C. Yosten, Missouri University of Science and TechnologyFollow

Abstract

Food intake is a complex, multifaceted process that involves the integration of numerous nutritional signals and behavioral outputs. Dozens of centrally acting peptide hormones that contribute to the control of appetite and food intake have been identified. Two recently described peptide hormones, neuronostatin and nesfatin-1, both act in the brain to induce anorexia, albeit through potentially different mechanisms. In this chapter, the central circuits mediating the anorexigenic effect of these two hormones, their interaction with the central melanocortin and oxytocin systems, and the physiological relevance of these hormones in appetite control are described and an integrated model of hypothalamic control of energy intake is presented. © 2013 Elsevier Inc.

Recommended Citation

G. L. Yosten, "Novel Neuropeptides in the Control of Food Intake. Neuronostatin and Nesfatin-1.," Vitamins and Hormones, vol. 92, pp. 1 - 25, Elsevier, Jan 2013.

The definitive version is available at https://doi.org/10.1016/B978-0-12-410473-0.00001-5

Department(s)

Biological Sciences

Keywords and Phrases

Metabolism; Nesfatin-1; Neuronostatin; Neuropeptide; Oxytocin; POMC

International Standard Serial Number (ISSN)

0083-6729

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2025 Elsevier, All rights reserved.

Publication Date

01 Jan 2013