Abstract

Borate bioactive glasses (BBGs) constitute the recently produced bioactive glasses (BGs) in the domain of bioactive materials, offering enhanced functionalities over conventional silicate and phosphate BGs. This advancement is primarily characterized by BBGs' rapid yet controllable degradation rates, superior bioactivity, and the ability to swiftly form a hydroxyapatite layer (HAP) upon interaction with physiological fluids. A distinguishing feature of BBGs lies in their customizability; doping with therapeutic metal ions tailors their bioactivity towards specific physiological responses, including promoting angiogenesis, antibacterial activity, and osteogenesis. This versatility of BBGs' applications extends to bone regeneration, wound healing, drug delivery systems, and potentially nerve regeneration. The emergence of BBGs marks a significant milestone in biomaterials research, setting new standards for the development of regenerative treatments and opening new avenues for medical applications. This literature review provides a comprehensive examination of BBGs, discussing their evolution, properties, clinical applications, comparative advantages, and future directions.

Department(s)

Biological Sciences

Second Department

Chemical and Biochemical Engineering

Keywords and Phrases

Antibacterial; Borate bioactive glasses; HAP; Metal-ion

International Standard Serial Number (ISSN)

0272-8842

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2024 Elsevier, All rights reserved.

Publication Date

01 Jan 2024

Download

Full Text Link

Share

 
COinS