In Vivo Analysis of Bioactivity of Borate Glass

Abstract

The 45S5 glass were implanted in the tibia of rats to assess the bioactive potential of the borate-based glass in comparison with the 45S5 control samples. Areas of new bone formation were detectable by difference in gray denisty in SEM-BSE images, as indicated by the arrows. Tibia with implanted particles of CABAL-17 borate glass, a bioinert material that does not convert to HAp, did not exhibited the intimate, surface-attached presence of newly formded bone. The results showed that the H6b composition borate-based glass behaved as a bioactive material in vivo similar to 45S5 glass.

Meeting Name

7th World Biomaterials Congress (2004: May 17-21, Sydney, Australia)

Department(s)

Biological Sciences

Second Department

Materials Science and Engineering

Keywords and Phrases

Biomaterials; Bone; Hydroxyapatite; Implants (surgical); Orthopedics; Protective coatings; Surface chemistry; Back scatter excitation (BSE); Bone formation; Dry-heating; Tibia of rats; Glass

International Standard Book Number (ISBN)

978-187704019-1

Document Type

Article - Conference proceedings

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2004 Society for Biomaterials, All rights reserved.

Publication Date

01 May 2004

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