Abstract
Cultures of murine erythroleukemic cells undergoing erythroid differentiation in response to induction by hexamethylene bisacetamide (HMBA) were exposed to 1180-MHz microwave (MW) radiation for 48 h while maintained at 37.4°C by variable-temperature air flow. Exposures at 1180 MHz were at 5.5, 11, and 22 mW/cm2 with a normalized specific absorption rate of 3.32 W/kg per mW/cm2. HMBA-induced control cells were incubated in a 37.4°C water bath. Mean cell doubling time was 16.5 h in both the irradiated cultures and the control cultures. About 65% of the cells of irradiated cultures and control cultures were benzidine-positive differentiated cells. Both the irradiated cultures and the control cultures contained approximately 58 μg of hemoglobin/mg total cytoplasmic protein. The absence of any change in these parameters suggests that MW radiation at 1180 MHz and similar frequencies exerts no effect on proliferation and differentiation of mammalian cells in the absence of hyperthermia.
Recommended Citation
R. F. Brown and S. V. Marshall, "Differentiation Of Murine Erythroleukemic Cells During Exposure To Microwave Radiation," Radiation Research, vol. 108, no. 1, pp. 12 - 22, JSTOR, Jan 1986.
The definitive version is available at https://doi.org/10.2307/3576965
Department(s)
Biological Sciences
International Standard Serial Number (ISSN)
0033-7587
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2023 JSTOR, All rights reserved.
Publication Date
01 Jan 1986
PubMed ID
3464992
