Abstract
The Energy Requirement for Biosynthesis Plays an Important Role in an Organism's Life History, as It Determines Growth Rate, and Tradeoffs with the Investment in Somatic Maintenance. This Energetic Trait is Different between Painted Lady (Vanessa Cardui) and Turkestan Cockroach (Blatta Lateralis) Due to the Different Life Histories. Butterfly Caterpillars (Holometabolous) Grow 30-Fold Faster, and the Energy Cost of Biosynthesis is 20 Times Cheaper, Compared to Cockroach Nymphs (Hemimetabolous). We Hypothesize that Physiologically the Difference in the Energy Cost is Partially Attributed to the Differences in Protein Retention and Turnover Rate: Species with Higher Energy Cost May Have a Lower Tolerance to Errors in Newly Synthesized Protein. Newly Synthesized Proteins with Errors Are Quickly Unfolded and Refolded, And/or Degraded and Resynthesized Via the Proteasomal System. Thus, Much Protein Output May Be Given over to Replacement of the Degraded New Proteins, So the overall Energy Cost on Biosynthesis is High. Consequently, the Species with a Higher Energy Cost for Biosyntheses Has Better Proteostasis and Cellular Resistance to Stress. Our Study Found that, Compared to Painted Lady Caterpillars, the Midgut Tissue of Cockroach Nymphs Has Better Cellular Viability under Oxidative Stresses, Higher Activities of Proteasome 20S, and a Higher RNA/growth Ratio, Supporting Our Hypothesis. This Comparative Study Offers a Departure Point for Better Understanding Life History Tradeoffs between Somatic Maintenance and Biosynthesis.
Recommended Citation
T. Iromini et al., "Link between Energy Investment in Biosynthesis and Proteostasis: Testing the Cost–Quality Hypothesis in Insects," Insects, vol. 14, no. 3, article no. 241, MDPI, Mar 2023.
The definitive version is available at https://doi.org/10.3390/insects14030241
Department(s)
Biological Sciences
Keywords and Phrases
energy; growth; life history; proteasome; somatic maintenance
International Standard Serial Number (ISSN)
2075-4450
Document Type
Article - Journal
Document Version
Final Version
File Type
text
Language(s)
English
Rights
© 2023 The Authors, All rights reserved.
Creative Commons Licensing
This work is licensed under a Creative Commons Attribution 4.0 License.
Publication Date
01 Mar 2023
