Whole-Genome Identification and Characterization of Bacterial Insertion Sequences using Bioinformatic Tools
Abstract
Insertion sequences are small mobile regions of DNA (transposable elements) found primarily in prokaryotes. The identification of insertion sequences in bacteria is a growing field of study because of their applications in evolution, genetics, and medicine. One of the first steps in characterizing the insertion sequences found in an organism is to perform a genome-wide survey to identify all insertion sequences using in silico methods. This includes a thorough scan of the genome to locate all copies of different families of insertion sequences and the identification of the key characteristics of each element. The results provide an extensive catalog of the insertion sequences which can be used to further other analyses or manipulation of the genome.
Recommended Citation
K. A. Bassett et al., "Whole-Genome Identification and Characterization of Bacterial Insertion Sequences using Bioinformatic Tools," Methods in Molecular Biology, vol. 2016, pp. 171 - 180, Humana Press Inc., Jun 2019.
The definitive version is available at https://doi.org/10.1007/978-1-4939-9570-7_16
Department(s)
Biological Sciences
Keywords and Phrases
Extremophilic bacteria; Genome survey; Insertion sequences; Transposable elements
International Standard Serial Number (ISSN)
1064-3745
Document Type
Book - Chapter
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2019 Springer Science+Business Media, LLC, All rights reserved.
Publication Date
01 Jun 2019
PubMed ID
31197719
