Genetic Dissection of Sleep Deprivation by Starvation in Drosophila

Presenter Information

Sarah Buckley

Department

Biological Sciences

Major

Biological Sciences

Research Advisor

Thimgan, Matthew S.

Advisor's Department

Biological Sciences

Funding Source

UM Research Board, Missouri; Missouri S&T OURE

Abstract

It is a common misconception that sleeping does not require energy. When flies are starved, they will disrupt their sleep time for waking behaviors. We have identified a gene, that when disrupted, accelerates the waking due to starvation. We don’t know which cells are responsible for this response. We will use a genetic strategy to find the cell and to understand the mechanism and the detection of waking due to starvation. If the mechanism can be understood, it may apply to understanding the causes of insomnia and decreased sleep.

Biography

Sarah is a sophomore from Richland, MO. She is studying Biological Sciences with an emphasis of Pre-Med and minors in Chemistry and Bio-Medical Engineering. On campus, Sarah is a Student Ambassador for the Admissions office, a member of Scrubs Pre-Health Group, an Honors Academy student, and she is currently working on an OURE with Dr. Thimgan.

Presentation Type

OURE Fellows Proposal Oral Applicant

Document Type

Presentation

Location

Turner Room

Presentation Date

11 Apr 2017, 9:20 am - 9:40 am

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Apr 11th, 9:20 AM Apr 11th, 9:40 AM

Genetic Dissection of Sleep Deprivation by Starvation in Drosophila

Turner Room

It is a common misconception that sleeping does not require energy. When flies are starved, they will disrupt their sleep time for waking behaviors. We have identified a gene, that when disrupted, accelerates the waking due to starvation. We don’t know which cells are responsible for this response. We will use a genetic strategy to find the cell and to understand the mechanism and the detection of waking due to starvation. If the mechanism can be understood, it may apply to understanding the causes of insomnia and decreased sleep.