Statistical Methods for Affymetrix Tiling Array Data
Miliken, George and Johnson, Dallas
Tiling arrays are a microarray technology currently being used for a variety of genomic and epigenomic applications, such as the mapping of transcription, DNA methylation, and histone modifications. Tiling arrays provide high-density coverage of a genome, or a genomic region, through the systematic and sequential placement of probes without regard to genome annotation. In this paper we compare the Affymetrix tiling array to the Affymetrix GeneChip® 3’ expression array and propose methods that address statistical and bioinformatic issues that accompany gene expression data that are generated from Affymetrix tiling arrays. Real data from the model organism Arabidopsis thaliana motivate this work and application
G. R. Olbricht et al., "Statistical Methods for Affymetrix Tiling Array Data," Proceedings of the Kansas State University Conference on Applied Statistics in Agriculture, 2009, Kansas State University, Jan 2009.
Applied Statistics in Agriculture: Proceedings of the Kansas State University Conference on Applied Statistics in Agriculture
Mathematics and Statistics
Keywords and Phrases
Microarray; Tiling Array; Differential Expression; ANOVA Model
Article - Conference proceedings
© 2009 Kansas State University, All rights reserved.
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