Title

Statistical Methods for Affymetrix Tiling Array Data

Editor(s)

Miliken, George and Johnson, Dallas

Abstract

Tiling arrays are a microarray technology currently being used for a variety of genomic and epigenomic applications, such as the mapping of transcription, DNA methylation, and histone modifications. Tiling arrays provide high-density coverage of a genome, or a genomic region, through the systematic and sequential placement of probes without regard to genome annotation. In this paper we compare the Affymetrix tiling array to the Affymetrix GeneChip® 3’ expression array and propose methods that address statistical and bioinformatic issues that accompany gene expression data that are generated from Affymetrix tiling arrays. Real data from the model organism Arabidopsis thaliana motivate this work and application

Meeting Name

Applied Statistics in Agriculture: Proceedings of the Kansas State University Conference on Applied Statistics in Agriculture

Department(s)

Mathematics and Statistics

Keywords and Phrases

Microarray; Tiling Array; Differential Expression; ANOVA Model

Document Type

Article - Conference proceedings

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2009 Kansas State University, All rights reserved.

Creative Commons Licensing

Creative Commons License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 License.

Share

 
COinS