N-Heterocyclic Carbenes in Organofluorine Chemistry
This short review summarizes the recent progress in organofluorinations catalyzed by N-heterocyclic carbene (NHC)-transition metal ion complexes. NHC-metal ion complexes are increasingly used in a variety of organic transformations, and they have opened up new opportunities, especially in the synthesis of organofluorine compounds. New advances in olefin metathesis, trifluoromethylations, Heck and Suzuki coupling, selective hydrodefluorination, and enantioselective synthesis of organofluorine compounds have been achieved through catalysis by NHC and their metal ion complexes. In this review, synthetic methods for various NHC-metal ion complexes and their applications in the synthesis of organofluorine compounds are comprehensively outlined.
P. Reddy et al., "N-Heterocyclic Carbenes in Organofluorine Chemistry," Journal of Organometallic Chemistry, Elsevier, Dec 2013.
The definitive version is available at http://dx.doi.org/10.1016/j.jorganchem.2013.04.051
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