Title

N-Heterocyclic Carbenes in Organofluorine Chemistry

Abstract

This short review summarizes the recent progress in organofluorinations catalyzed by N-heterocyclic carbene (NHC)-transition metal ion complexes. NHC-metal ion complexes are increasingly used in a variety of organic transformations, and they have opened up new opportunities, especially in the synthesis of organofluorine compounds. New advances in olefin metathesis, trifluoromethylations, Heck and Suzuki coupling, selective hydrodefluorination, and enantioselective synthesis of organofluorine compounds have been achieved through catalysis by NHC and their metal ion complexes. In this review, synthetic methods for various NHC-metal ion complexes and their applications in the synthesis of organofluorine compounds are comprehensively outlined.

Department(s)

Chemistry

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2013 Elsevier, All rights reserved.


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