Title

The Use of Nanoparticles and Bioglass in Inhibiting Legi

Department

Biological Sciences

Major

Biology

Research Advisor

Westenberg, David J.

Advisor's Department

Biological Sciences

Funding Source

OURE Fellows and EPA

Abstract

Legionnaires' disease is a form of pneumonia caused by coming into contact with Legionella pneumophila. Exposure typically occurs when humans use showerheads, sink faucets, or large plumbing systems that the bacterium has colonized. This public health crisis has led researchers to find ways to help eradicate Legionella from these water systems, however many of the current methods are not sufficient in preventing recolonization and can lead to corrosion of water pipes. Given this, the project at hand aims to use two different methods to tackle this issue. The first method involves testing copper nanoparticles as a viable alternative to these solutions by determining the concentration and ideal size of nanoparticles needed to kill the bacteria. Additionally, we will use bioglass doped with anti-bacterial metals to test its effectiveness in inhibiting biofilm formation by the bacteria. All studies will be conducted using an avirulent strain of the bacteria (LP02).

Biography

Gabrielle Hightower is a junior from Kansas City, Missouri majoring in Biology and Psychology. She has participated in Missouri S&T's FYRE, OURE, and OURE Fellows programs as well as the Summer Undergraduate Research Fellowship through the University of Arkansas for Medical Sciences. She plans on sing this experience once she graduates to obtain her PhD and conduct research. When she is not conducting research, she is an active member of Chi Omega, Missouri S&T Ballet and Dance Club, Blue Key, and SCRUBS.

Presentation Type

OURE Fellows Proposal Oral Applicant

Document Type

Presentation

Location

Missouri Room

Presentation Date

14 Apr 2021, 10:00 am - 10:30 am

This document is currently not available here.

Share

COinS
 
Apr 14th, 10:00 AM Apr 14th, 10:30 AM

The Use of Nanoparticles and Bioglass in Inhibiting Legi

Missouri Room

Legionnaires' disease is a form of pneumonia caused by coming into contact with Legionella pneumophila. Exposure typically occurs when humans use showerheads, sink faucets, or large plumbing systems that the bacterium has colonized. This public health crisis has led researchers to find ways to help eradicate Legionella from these water systems, however many of the current methods are not sufficient in preventing recolonization and can lead to corrosion of water pipes. Given this, the project at hand aims to use two different methods to tackle this issue. The first method involves testing copper nanoparticles as a viable alternative to these solutions by determining the concentration and ideal size of nanoparticles needed to kill the bacteria. Additionally, we will use bioglass doped with anti-bacterial metals to test its effectiveness in inhibiting biofilm formation by the bacteria. All studies will be conducted using an avirulent strain of the bacteria (LP02).