Selective Laser Sintering and Freeze Extrusion Fabrication of Scaffolds for Bone Repair using 13-93 Bioactive Glass: A Comparison
13-93 glass is a third-generation bioactive material which accelerates the bone’s natural ability to heal by itself through bonding with surrounding tissues. It is an important requirement for synthetic scaffolds to maintain their bioactivity and mechanical strength with a porous internal architecture comparable to that of a human bone. Additive manufacturing technologies provide a better control over design and fabrication of porous structures than conventional methods. In this paper, we discuss and compare some of the common aspects in the scaffold fabrication using two such processes, viz. selective laser sintering (SLS) and freeze extrusion fabrication (FEF). Scaffolds fabricated using each process were structurally characterized and microstructure analysis was performed to study process differences. Compressive strength higher than that of human trabecular bone was achieved using SLS process and strength almost comparable to that of human cortical bone was achieved using FEF process.
K. C. Kolan et al., "Selective Laser Sintering and Freeze Extrusion Fabrication of Scaffolds for Bone Repair using 13-93 Bioactive Glass: A Comparison," Proceedings of the 21st Annual International Solid Freeform Fabrication Symposium (2010, Austin, TX), pp. 876 - 883, University of Texas at Austin, Aug 2010.
21st Annual International Solid Freeform Fabrication Symposium -- An Additive Manufacturing Conference (2010: Aug. 9-11, Austin, TX)
Mechanical and Aerospace Engineering
Intelligent Systems Center
Article - Conference proceedings
11 Aug 2010
The research work was funded by National Science Foundation under NSF SBIR phase I award #0912019 to Mo-Sci Corporation, as well as by the Intelligent Systems Center and the Center for Bone and Tissue Repair and Regeneration at Missouri University of Science and Technology.