Characterization of the Conversion of Bone Cement and Borate Bioactive Glass Composites
Borate bioactive glass 13-93B3 converts into an osteoconductive hydroxyapatite-like material in a liquid medium. In this study, 13-93B3 was incorporated into a commercial PMMA (poly(methyl methacrylate)) bone cement, and the conversion of the glass into a precipitate in solution was investigated with scanning electron microscopy, energy dispersive X-ray spectroscopy, Fourier transform infrared (spectroscopy)-attenuated total reflection, and micro-Raman spectroscopy. Glass particles of 5, 33, and 100 µm diameter were each mixed with the PMMA cement to create 20, 30, and 40% glass-loaded composites. Precipitate formation was found to be a calcium-deficient apatite partially substituted with magnesium ions that resembles native bone material and would ideally encourage bone growth better than stoichiometric hydroxyapatite. Composites of bone cement and 13-93B3 show promise as a means of encouraging bone attachment to the surface of the bone cement.
K. A. Cole et al., "Characterization of the Conversion of Bone Cement and Borate Bioactive Glass Composites," Journal of Biomedical Materials Research - Part B Applied Biomaterials, vol. 108, no. 4, pp. 1580 - 1591, John Wiley & Sons Inc., May 2020.
The definitive version is available at https://doi.org/10.1002/jbm.b.34505
Materials Science and Engineering
Keywords and Phrases
Bioactive Glass; Bone Cement-PMMA, Acrylic; Composite/Hard Tissue; Hydroxy(1)lapatite; Surface Characterization
International Standard Serial Number (ISSN)
Article - Journal
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01 May 2020