Keywords and Phrases
Insertion Sequences; Transposable Elements
"Insertion sequences (IS) are the smallest prokaryotic transposable elements. These mobile genes are highly diverse in size and structure, making them difficult to study. The transposition activity of insertion sequences has a significant role in evolution by enabling genomic plasticity via genome rearrangements. Insertion sequences are largely uncharacterized and thus methods to improve the ability to accurately identify, annotate, and infer genomic impact of insertion sequences is limited. A sequential set of methods using readily available genomic and bioinformatic tools was developed to accurately identify insertion sequences. This method was used to perform an entire genome survey of Halanaerobium hydrogeniformans to identify and characterize all insertion sequences. After characterization insertion sequence activity is inferred, including transposition capability, element interaction, and insertion sequence evolution"--Abstract, page iii.
Frank, Ronald L.
Mormile, Melanie R.
Westenberg, David J.
M.S. in Applied and Environmental Biology
Missouri University of Science and Technology
xii, 86 pages
© 2019 Kody Austin Bassett, All rights reserved.
Thesis - Open Access
Electronic OCLC #
Bassett, Kody Austin, "A genome wide survey of the insertion sequences in Halanaerobium hydrogeniformans, a haloalkaliphilic anaerobic bacterium" (2019). Masters Theses. 7878.