Masters Theses

Keywords and Phrases

Insertion Sequences; Transposable Elements

Abstract

"Insertion sequences (IS) are the smallest prokaryotic transposable elements. These mobile genes are highly diverse in size and structure, making them difficult to study. The transposition activity of insertion sequences has a significant role in evolution by enabling genomic plasticity via genome rearrangements. Insertion sequences are largely uncharacterized and thus methods to improve the ability to accurately identify, annotate, and infer genomic impact of insertion sequences is limited. A sequential set of methods using readily available genomic and bioinformatic tools was developed to accurately identify insertion sequences. This method was used to perform an entire genome survey of Halanaerobium hydrogeniformans to identify and characterize all insertion sequences. After characterization insertion sequence activity is inferred, including transposition capability, element interaction, and insertion sequence evolution"--Abstract, page iii.

Advisor(s)

Frank, Ronald L.

Committee Member(s)

Mormile, Melanie R.
Westenberg, David J.

Department(s)

Biological Sciences

Degree Name

M.S. in Applied and Environmental Biology

Publisher

Missouri University of Science and Technology

Publication Date

Spring 2019

Pagination

xii, 86 pages

Note about bibliography

Includes bibliographic references (pages 79-85).

Rights

© 2019 Kody Austin Bassett, All rights reserved.

Document Type

Thesis - Open Access

File Type

text

Language

English

Thesis Number

T 11518

Electronic OCLC #

1105154958

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