Keywords and Phrases
Bimetallic Nanoparticles; Cancer Treatment; Radioactive Nanoparticles; Research Nuclear Reactor; Synthesis; Water Radiolysis
In this work, the synthesis of radioactive nanostructures by water radiolysis was studied. The irradiation processes were done in the Missouri University of Science and Technology research nuclear reactor (MSTR).
Radioactive gold nanoparticles (AuNPs) were synthesized from aqueous solutions containing the metal salt precursors by radiolysis of water. Seven different samples were irradiated at 200kW of thermal power for 0.5, 1, 3, 5, 10, 30, and 60 minutes. The average sizes of the obtained nanoparticles ranged from 3 nm to 400 nm, it was found that the particle size decreased with the irradiation time. Some agglomerations of particles were found in each solution after the irradiation process. With this research, it was possible to synthesize, in a single step, radioactive AuNPs with the appropriate characteristics to be used in imaging diagnosis and cancer radiation therapy.
Radioactive bimetallic nanoparticles of silver and gold (Au/Ag BMNPs) were synthesized from aqueous solutions containing the metal salt precursors by radiolysis of water. Four samples with different Au/Ag concentration (30/70, 50/50, 70/30, and 0/100 by volume percentage) were irradiated at 10kW of thermal power for 3 minutes. The obtained nanoparticles showed (Au)core-shell(Ag) structure as well as alloyed metal structure depending on the solution concentration. It was found that the alloyed metal nanoparticles presented a faced centered cubic crystal structure with lattice parameter of 4.082 ± 0.001 Å and a chemical composition of 70.21 ± 0.01 wt% Au and 28.59 ± 0.01 wt% Ag.
Castano Giraldo, Carlos Henry
Schlegel, Joshua P.
Smith, Joseph D.
Mining and Nuclear Engineering
M.S. in Nuclear Engineering
Missouri University of Science and Technology
Journal article titles appearing in thesis/dissertation
- Synthesis of Radioactive Gold Nanoparticles Using a Research Nuclear Reactor
- Production of Bimetallic Gold-Silver Nanoparticles in a Research Nuclear Reactor
- Theoretical Estimation of The Total Absorbed Dose in MSTR
xii, 87 pages
© 2016 Maria Camila Garcia Toro, All rights reserved.
Thesis - Open Access
Electronic OCLC #
Garcia Toro, Maria Camila, "Synthesis of Radioactive Nanostructures in a Research Nuclear Reactor" (2016). Masters Theses. 7813.