Clustering Algorithms in Biomedical Research: A Review

Author

Rui Xu, Missouri University of Science and TechnologyFollow
Donald C. Wunsch, Missouri University of Science and TechnologyFollow

Abstract

Applications of clustering algorithms in biomedical research are ubiquitous, with typical examples including gene expression data analysis, genomic sequence analysis, biomedical document mining, and MRI image analysis. However, due to the diversity of cluster analysis, the differing terminologies, goals, and assumptions underlying different clustering algorithms can be daunting. Thus, determining the right match between clustering algorithms and biomedical applications has become particularly important. This paper is presented to provide biomedical researchers with an overview of the status quo of clustering algorithms, to illustrate examples of biomedical applications based on cluster analysis, and to help biomedical researchers select the most suitable clustering algorithms for their own applications.

Recommended Citation

R. Xu and D. C. Wunsch, "Clustering Algorithms in Biomedical Research: A Review," IEEE Reviews in Biomedical Engineering, vol. 3, pp. 120 - 154, Institute of Electrical and Electronics Engineers (IEEE), Jan 2010.

The definitive version is available at https://doi.org/10.1109/RBME.2010.2083647

Department(s)

Electrical and Computer Engineering

International Standard Serial Number (ISSN)

1937-3333

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2010 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.

Publication Date

01 Jan 2010