Thermochemical Isotope Effects III
Hydrogen-deuterium exchange between methanol and water at 25°
Enthalpies of solution of small amounts of D2O and CH3OD in mixtures of methanol and water at 25° have been interpreted in terms of the equilibrium (CH3OH + HDO = CH3OD + H2O). The enthalpy of this reaction appears to vary from -100 cal/mol in methanol to -200 cal/mol in water. Approximations are introduced to account for this variation. “Best” estimates of the equilibrium constant are 0.6 in methanol and 0.6-0.7 in water.
G. L. Bertrand and T. E. Burchfield, "Thermochemical Isotope Effects III," Journal of Physical Chemistry, American Chemical Society (ACS), Jan 1975.
The definitive version is available at http://dx.doi.org/10.1021/j100582a014
Article - Journal
© 1975 American Chemical Society (ACS), All rights reserved.