Electrospinning of PEGylated Polyamidoamine Dendrimer Fibers

Abstract

Polyamidoamine (PAMAM) dendrimers have emerged as an important class of nanostructured materials and have found a broad range of applications. There is also an ongoing effort to synthesize higher-complexity structures using PAMAM dendrimers as enabling building blocks. Herein, we report for the first time the fabrication of electrospun nanocomposite fibers composed of dendrimer derivatives, namely PEGylated PAMAM dendrimers, blended with a small amount of high-molecular-weight polyethylene oxide (PEO). Morphological features and mechanical properties of the resulting dendrimer fiber mats were assessed.

Department(s)

Chemical and Biochemical Engineering

Comments

This work was supported, in part, by the National Science Foundation CAREER award ( CBET0954957 ) and National Institutes of Health ( R01EY024072 ).

Keywords and Phrases

Dendrimer; Electrospinning; Fast Fourier transform; Nanofiber; PEGylation

International Standard Serial Number (ISSN)

0928-4931

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2015 Elsevier Ltd, All rights reserved.

Publication Date

01 Nov 2015

PubMed ID

26249580

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