Soap Lake is a meromictic, alkaline (∼pH 9.8) and saline (∼14-140 g liter-1) lake located in the semiarid area of eastern Washington State. Of note is the length of time it has been meromictic (at least 2000 years) and the extremely high sulfide level (∼140 mM) in its monimolimnion. As expected, the microbial ecology of this lake is greatly influenced by these conditions. A bacterium, Halanaerobium hydrogeniformans, was isolated from the mixolimnion region of this lake. Halanaerobium hydrogeniformans is a haloalkaliphilic bacterium capable of forming hydrogen from 5- and 6-carbon sugars derived from hemicellulose and cellulose. Due to its ability to produce hydrogen under saline and alkaline conditions, in amounts that rival genetically modified organisms, its genome was sequenced. This sequence data provides an opportunity to explore the unique metabolic capabilities of this organism, including the mechanisms for tolerating the extreme conditions of both high salinity and alkalinity of its environment.

Meeting Name

Halophiles: The International Conferenece on Halophilic Microorganisms (2013: Jun. 23-27, Storrs, CT)


Biological Sciences

Keywords and Phrases

ABC Transporter; Cellobiose; Flavodoxin; Glycerol; Glycosyltransferase; Guanosine Phosphate; Lactate Dehydrogenase; Phosphotransferase; Ribosome RNA; Amino Acid Sequence; Biogenesis; Biomass Fermentation; Cell Motility; Cell Signaling Assay; Ecology; Fatty Acid Synthesis; Halanaerobium hydrogeniformans; Halophilic Bacterium; Metabolism; Methanogenesis; Microbial Genome; Nonhuman; Nucleotide Sequence; Osmotic Stress; Sulfate Reducer; United States; Alkaliphile; Biohydrogen; Genome Analysis; Halotolerant; Soap Lake

Geographic Coverage

Soap Lake, Washington

International Standard Serial Number (ISSN)


Document Type

Article - Conference proceedings

Document Version

Final Version

File Type





© 2014 Frontiers Media, All rights reserved.

Creative Commons Licensing

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.

Publication Date

01 Nov 2014

PubMed ID