Location
Havener Center, Miner Lounge / Wiese Atrium, 1:30pm-3:30pm
Start Date
4-2-2026 1:30 PM
End Date
4-2-2026 3:30 PM
Presentation Date
April 2, 2026; 1:30pm-3:30pm
Description
The development of highly sensitive real-time sensing platforms for selectively detecting dopamine (DA) and norepinephrine (NE) is of significant clinical importance since these are closely associated with several neurodegenerative disorders. Herein, we report copper telluride (Cu₂Te) nanostructure as a bifunctional electrocatalyst for the simultaneous detection of dopamine and norepinephrine. Cu₂Te exhibits excellent electrocatalytic activity toward both DA and NE oxidation, as demonstrated by detailed electrochemical measurements. High sensitivities of 24 and 40 µA cm⁻² µM⁻¹ for DA and NE, respectively, were obtained with a wide linear detection range of 10–200 nM and low limit of detection (LOD), 31 nM for DA and 1.98 nM for NE. The sensor's performance is within physiologically relevant concentration ranges as found in peripheral tissue fluids and shows high selectivity against common interfering biomolecules. This work highlights the potential of Cu₂Te nanostructures as efficient platform for detecting neurochemicals in real-time with point-of-care diagnostic devices.
Biography
Amitav Sen is a 3rd year Ph.D. student in Chemistry at Missouri S&T. He earned his B.Sc. and M.Sc degrees in Applied Chemistry and Chemical Engineering from the University of Chittagong, Bangladesh. Currently, he serves as a Graduate Teaching Assistant (GTA) and Graduate Research Assistant (GRA) in the Department of Chemistry, working under the supervision of Dr. Manashi Nath. His campus startup, NeuroTechSense, was recognized as Champion and Audience Favorite at the Miner Tank Innovation Pitch Showdown and earned the RedBud Venture Capital Award as Second Runner-Up in the Miner Accelerator Program. During his Master's studies, he was awarded the National Science and Technology (NST) Fellowship (2022) for his research on the biosynthesis of zinc oxide nanoparticles and their biomedical applications. His doctoral research focuses on the development of electrocatalysts for sensor applications, particularly in advancing nonenzymatic biosensors for neurotransmitter detection. His work aims to address challenges in neurological disease diagnostics by designing and synthesizing stable and highly sensitive nanomaterial-based biosensors capable of real-time neurochemical monitoring.
Meeting Name
2026 - Miners Solving for Tomorrow Research Conference
Department(s)
Chemistry
Document Type
Poster
Document Version
Final Version
File Type
event
Language(s)
English
Rights
© 2026 The Authors, All rights reserved
Included in
Transition Metal Chalcogenide as Multifunctional Biosenser to Detect Neurochemicals
Havener Center, Miner Lounge / Wiese Atrium, 1:30pm-3:30pm
The development of highly sensitive real-time sensing platforms for selectively detecting dopamine (DA) and norepinephrine (NE) is of significant clinical importance since these are closely associated with several neurodegenerative disorders. Herein, we report copper telluride (Cu₂Te) nanostructure as a bifunctional electrocatalyst for the simultaneous detection of dopamine and norepinephrine. Cu₂Te exhibits excellent electrocatalytic activity toward both DA and NE oxidation, as demonstrated by detailed electrochemical measurements. High sensitivities of 24 and 40 µA cm⁻² µM⁻¹ for DA and NE, respectively, were obtained with a wide linear detection range of 10–200 nM and low limit of detection (LOD), 31 nM for DA and 1.98 nM for NE. The sensor's performance is within physiologically relevant concentration ranges as found in peripheral tissue fluids and shows high selectivity against common interfering biomolecules. This work highlights the potential of Cu₂Te nanostructures as efficient platform for detecting neurochemicals in real-time with point-of-care diagnostic devices.

Comments
Advisor: Manashi Nath, nathm@mst.edu