A radiolabeled protein composition adapted for radiation therapy which comprises a radioisotope and a protein material containing about 6 or more percent amino acids which have a sulfhydryl-containing side chain. A method for carrying out radiation synovectomy of arthritic joints. Rhenium radiolabeled protein micro- spheres are administered which contain cysteine and other amino acids. A method for radiolabeling a protein composition whereby the composition is treated with a reducing agent capable of reducing disulfides to sulfhydryls prior to radiolabeling.
D. E. Day et al., "Radiolabeled Protein Composition and Method for Radiation Synovectomy," The Curators of the University of Missouri, Apr 1995.
Materials Science and Engineering
Patent Application Number
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