Masters Theses

Abstract

"In this work, an experimental design was employed to investigate the effects of different operating conditions on the isomerization of lactose to lactulose by using strong basic anion exchange resin (AMBERLITE-IRA 402). Temperature, resin/lactose mass ratio and pH were considered to be the three factors affecting the conversion of lactose. Box-Behnken design was then used to optimize the operating conditions for maximum response and also to study the various interaction and main effects of the factors. The analysis of variance (ANOVA) of the experimental data showed a high correlation coefficient R² (0.99) and a low root mean square error (2.84) values for the second order regression model for the experimental design, indicating the good predictive nature of the model. The results gave an operating condition of temperature = 80.8⁰C, resin/lactose mass ratio = 0.371 and pH = 10.3 for maximum response.

A kinetic model was deduced on the basis of Langmuir-Hinshelwood-Hougen-Watson formulation and the experimental data was later fit to the model by using least square approximation to estimate the activation energy (Ea), pre-exponential factor (A0) and the adsorption coefficient (K₁). The effect of resin bead diameter was also studied and the results indicated that the bead diameter of the as-received resin is sufficiently small to eliminate internal diffusion resistances."--Abstract, page iii.

Advisor(s)

Sitton, Oliver C., 1951-

Committee Member(s)

Samaranayake, V. A.
Book, Neil L.

Department(s)

Chemical and Biochemical Engineering

Degree Name

M.S. in Chemical Engineering

Publisher

Missouri University of Science and Technology

Publication Date

Fall 2010

Pagination

xvi, 116 pages

Note about bibliography

Includes bibliographical references.

Rights

© 2010 Arvind Nanduri, All rights reserved.

Document Type

Thesis - Open Access

File Type

text

Language

English

Subject Headings

Anions
Chemical kinetics -- Mathematical models
Ion exchange resins
Isomerization
Lactose
Lactulose

Thesis Number

T 9716

Print OCLC #

724097176

Electronic OCLC #

724099545

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