Title

Optofluidic Oxygen Sensor with Simple Structure and Low-Cost Materials

Abstract

A simple, low-cost optofluidic sensor platform composed of ubiquitous materials is developed. The main device structure consists of an extremely simple assembly of readily available materials including metal wires and polymeric microbore tubing. We demonstrate that the quenching-based fluorescence oxygen sensing, as a model system, can be conducted with this cost-effective device platform. This 1-dimensional "lab-in-tube" configuration has a high potential for conducting a streamlined bioanalytical procedures, such as immunoassays including the enzyme-linked-immunosorbent assay (ELISA), with convenience for fluidic manipulation. Its potential capability includes surface-enhanced signals, multi-modality sensing and simultaneous/multiple assays. We anticipate the proposed device platform to make one of viable candidates for future point-of-care (POC) screening devices.

Department(s)

Electrical and Computer Engineering

Keywords and Phrases

Assays; Cost effectiveness; Costs; Fluorescence; Oxygen; Oxygen sensors; Ruthenium compounds; Enzyme linked immunosorbent assay; Fluidic manipulation; High potential; Optofluidic sensors; Potential capability; Ruthenium complexes; Screening devices; Simple structures; Tubing; Lab-in-tube; Ruthenium-complex; Tube

International Standard Serial Number (ISSN)

1546-198X

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2015 American Scientific Publishers, All rights reserved.

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