Optofluidic Oxygen Sensor with Simple Structure and Low-Cost Materials
A simple, low-cost optofluidic sensor platform composed of ubiquitous materials is developed. The main device structure consists of an extremely simple assembly of readily available materials including metal wires and polymeric microbore tubing. We demonstrate that the quenching-based fluorescence oxygen sensing, as a model system, can be conducted with this cost-effective device platform. This 1-dimensional "lab-in-tube" configuration has a high potential for conducting a streamlined bioanalytical procedures, such as immunoassays including the enzyme-linked-immunosorbent assay (ELISA), with convenience for fluidic manipulation. Its potential capability includes surface-enhanced signals, multi-modality sensing and simultaneous/multiple assays. We anticipate the proposed device platform to make one of viable candidates for future point-of-care (POC) screening devices.
S. Gong and C. Kim, "Optofluidic Oxygen Sensor with Simple Structure and Low-Cost Materials," Sensor Letters, vol. 13, no. 8, pp. 679-682, American Scientific Publishers, Aug 2015.
The definitive version is available at https://doi.org/10.1166/sl.2015.3478
Electrical and Computer Engineering
Keywords and Phrases
Assays; Cost effectiveness; Costs; Fluorescence; Oxygen; Oxygen sensors; Ruthenium compounds; Enzyme linked immunosorbent assay; Fluidic manipulation; High potential; Optofluidic sensors; Potential capability; Ruthenium complexes; Screening devices; Simple structures; Tubing; Lab-in-tube; Ruthenium-complex; Tube
International Standard Serial Number (ISSN)
Article - Journal
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