Doctoral Dissertations

Jie Zhang

Keywords and Phrases

CFD; Droplets; Finite Element Method; Magnetic field; Microfluidics; Microparticles

Abstract

“Magnetic particles and droplets have been used in a wide range applications including biomedicine, biological analysis and chemical reaction. The manipulation of magnetic microparticles or microdroplets in microscale fluid environments is one of the most critical processes in the systems and platforms based on microfluidic technology. The conventional methods are based on magnetic forces to manipulate magnetic particles or droplets in a viscous fluid.

In contrast to conventional magnetic separation method, several recent experimental and theoretical studies have demonstrated a different way to manipulate magnetic non-spherical particles by using a uniform magnetic field in the microchannel. However, the fundamental mechanism behind this method is not fully understood. In this research, we aims to use numerical and experimental methods to explore and investigate manipulation of microparticles and microdroplets in the microfluidics by using a uniform magnetic field. In the first part, rotational dynamics of elliptical particles in a simple shear flow is numerically investigated; then, lateral migration of elliptical particles in a plane Poiseuille flow is numerically investigated; The third part compares the rotational dynamics of paramagnetic and ferromagnetic elliptical particles particles in a simple shear flow; in the fourth part, particle-particle interactions and relative motions of a pair of magnetic elliptical particles in a quiescent flow are numerically investigated; magnetic separation of magnetic microdroplets by the uniform magnetic field is proposed in the fifth part.

The methods demonstrated in this research not only develop numerical and experimental way to understand the fundamental transport properties of magnetic particles and droplets in microscale fluid environments, but also provide a simple and efficient method for the separation of microdroplets in microfluidic device, which can impact biomedical and bio-medicine technologies”--Abstract, page iv.

Advisor(s)

Wang, Cheng

Committee Member(s)

Isaac, Kakkattukuzhy M.
Homan, Kelly
Chandrashekhara, K.
He, Xiaoming

Department(s)

Mechanical and Aerospace Engineering

Degree Name

Ph. D. in Mechanical Engineering

Comments

The authors gratefully acknowledge the support from the Department of Mechanical and Aerospace Engineering (MAE) and the Center for Biomedical Research (CBR) at Missouri University of Science and Technology. This work is partially supported by the National Science Foundation (Grant No. DMS-1818642).

Publisher

Missouri University of Science and Technology

Publication Date

Summer 2020

Journal article titles appearing in thesis/dissertation

  • Study of rotation of ellipsoidal particles in combined simple shear flow and magnetic fields
  • Numerical study of lateral migration of elliptical magnetic microparticles in microchannels in uniform magnetic fields
  • Numerical investigation of rotational dynamics of elliptical magnetic microparticles in shear flows
  • Dynamics of a pair of ellipsoidal microparticles under uniform magnetic fields
  • Migration of ferrofluid droplets in shear flow under a uniform magnetic field

Pagination

xv, 154 pages

Note about bibliography

Includes bibliographic references.

Rights

© 2020 Jie Zhang, All rights reserved.

Document Type

Dissertation - Open Access

File Type

text

Language

English

Thesis Number

T 11763

Electronic OCLC #

1198498918

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