Abstract
Several indan, tetralin and benzosuberan derivatives of diverse polarities were enantio-resolved by the use of sulfated β-cyclodextrins (CDs) or mixtures of sulfated β-CDs and γ-CD as chiral additives in capillary electrophoresis. Mixtures of sulfated 13-CDs and hydroxypropy1 β- CDs were also successfully utilized for enantiomeric and diastereomeric separations of some of the tetralin derivatives with two stereogenic centers. Both neutral and anionic analytes were resolved in the reversed electrophoretic polarity mode. Cationic amino derivatives of indan and tetralin were enantio-resolved in the conventional electrophoretic polarity mode.
Recommended Citation
K. H. Gahm et al., "Chiral Separations of Indan, Tetralin and Benzosuberan Derivatives by Capillary Electrophoresis," Journal of Chromatography A, vol. 793, no. 1, pp. 135 - 143, Elsevier, Jan 1998.
The definitive version is available at https://doi.org/10.1016/S0021-9673(97)00802-9
Department(s)
Chemistry
Keywords and Phrases
Benzosuberan derivatives; Enantiomer separation; Indan derivatives; Tetralin derivatives
International Standard Serial Number (ISSN)
0021-9673
Document Type
Article - Journal
Document Version
Citation
File Type
text
Language(s)
English
Rights
© 2024 Elsevier, All rights reserved.
Publication Date
09 Jan 1998
Comments
Environmental Protection Agency, Grant R823360-01-0