Title

Cost Effective Surface Functionalization of Gold Nanoparticles with a Mixed DNA and PEG Monolayer for Nanotechnology Applications

Abstract

A cost effective and generally applicable co-functionalization of gold nanoparticles with a mixed DNA and PEG polymers is reported. Compared to the pure DNA functionalization method, this protocol uses a much smaller amount of thiol-DNA to achieve a similar binding efficacy of gold nanoparticles with DNA origami nanostructures. The lower consumption of DNA provides a scaling-up potential for the application of DNA-nanoparticle conjugates in nanotechnology.

Department(s)

Chemistry

Keywords and Phrases

Cost Effectiveness; Fiber Optic Sensors; Gold; Metal Nanoparticles; Nanoparticles; Nanostructures; Nanotechnology; Binding Efficacy; Dna Nanoparticles; Dna Origamis; Functionalizations; Surface Functionalization

International Standard Serial Number (ISSN)

2046-2069

Document Type

Article - Journal

Document Version

Citation

File Type

text

Language(s)

English

Rights

© 2017 Royal Society of Chemistry, All rights reserved.

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