In Vivo and in Vitro Aging of Orthopedic Aluminas
The flexural strength, microstructure and relative Ca and Si concentration at the surface of two commercial orthopedic aluminas were studied before and after aging up to 52 weeks in simulated body fluids or in subcutaneous implantation in rodents. There was no significant reduction in flexural strength after aging, but there was evidence of Ca and Si dissolution from the external grain boundary surfaces, particularly for specimens aged in demineralized water. No change occurred in the Ca and Si concentrations within the specimen's bulk during either in vivo or in vitro aging.
A. Fahr et al., "In Vivo and in Vitro Aging of Orthopedic Aluminas," Journal of Biomedical Materials Research, vol. 17, no. 3, pp. 395-410, Wiley-Blackwell, May 1983.
The definitive version is available at http://dx.doi.org/10.1002/jbm.820170302
Materials Science and Engineering
Keywords and Phrases
Biomedical Engineering - Surgical Implants; Calcium And Alloys; Silicon And Alloys; Orthopedics; Alumina; Support, U.S. Gov't, P.H.S.
International Standard Serial Number (ISSN)
Article - Journal
© 1983 Wiley-Blackwell, All rights reserved.