Title

Biofilm Formation and the Antibacterial Properties of Silicon Nitride and Other Biomaterials

Presenter Information

Justin Lovelady

Department

Biological Sciences

Major

Biology

Research Advisor

Westenberg, David J.

Advisor's Department

Biological Sciences

Funding Source

Amedica

Abstract

The medical applications of antibacterial biomaterials have made great strides since the field’s beginning. With new material being produced for surgical implantation, questions of bodily reactions to these biomaterials arise. As a foreign substance is placed into the body a biofilm may accumulate on the surface, which can then lead to severe infections and become difficult to treat. One such material is an antibacterial silicon nitride polymer designed for orthopedic and spinal implants. Using a CDC Biofilm Reactor the testing of these new materials has been accomplished to accurately predict the antibacterial properties of each material. After the reactor is inoculated, samples are taken after 4, 24, 48 and 72 hours and tested for growth of biofilms. Our preliminary data indicates an initial reduction in biofilm formation with some material. With the successful completion of this project, a more effective biomaterial could be found and made readily available for safe and practical use in the human body.

Biography

Justin Lovelady is in his fourth year at Missouri University of Science and Technology. He is studying Biology with emphasis in Pre-Med and pursuing a minor in Chemistry. He is a member of Delta Tau Delta Fraternity, a member of the Missouri S&T Jazz Band, and a Photographer for RollaMo Yearbook. He plans to attend Graduate School at Missouri S&T and later plans on going to Medical School in Chicago at Midwestern University.

Research Category

Sciences

Presentation Type

OURE Fellows Proposal Oral Applicant

Document Type

Presentation

Award

Fellows 14-15 Awarded

Location

Turner Room

Presentation Date

16 Apr 2014, 1:40 pm - 2:00 pm

This document is currently not available here.

Share

COinS
 
Apr 16th, 1:40 PM Apr 16th, 2:00 PM

Biofilm Formation and the Antibacterial Properties of Silicon Nitride and Other Biomaterials

Turner Room

The medical applications of antibacterial biomaterials have made great strides since the field’s beginning. With new material being produced for surgical implantation, questions of bodily reactions to these biomaterials arise. As a foreign substance is placed into the body a biofilm may accumulate on the surface, which can then lead to severe infections and become difficult to treat. One such material is an antibacterial silicon nitride polymer designed for orthopedic and spinal implants. Using a CDC Biofilm Reactor the testing of these new materials has been accomplished to accurately predict the antibacterial properties of each material. After the reactor is inoculated, samples are taken after 4, 24, 48 and 72 hours and tested for growth of biofilms. Our preliminary data indicates an initial reduction in biofilm formation with some material. With the successful completion of this project, a more effective biomaterial could be found and made readily available for safe and practical use in the human body.