Title

Evaluation of a Biological Glucose Concentration-sengings iGEM Part

Presenter Information

Logan Sauerbrei

Department

Biological Sciences

Major

Biological Sciences

Research Advisor

Westenberg, David J.

Advisor's Department

Biological Sciences

Abstract

In the bodies of people with type one diabetes, the body has lost the ability recognize and respond to glucose concentration in the blood. This leads to an accumulation of glucose is the blood stream. High blood glucose concentrations damage the body in many ways. One theoretical solution to these issues would be to use microbes to replace both of these functions. The ability to recognize glucose concentration is the first part that needs to be developed. Once a part can successfully recognize different glucose concentrations, it can be used in coordination with other parts. Contained in the iGEM registry is such a glucose-concentration sensing part. However, the concentration needed for its activation is unknown. This specific concentration should be discovered, and mutants of the part that respond to different concentrations of glucose should be produced.

Biography

Logan is a junior studying biological science. He was diagnosed with type one diabetes in high school, and wants to see it cured.

Research Category

Research Proposals

Presentation Type

Poster Presentation

Document Type

Poster

Location

Upper Atrium/Hallway

Presentation Date

06 Apr 2011, 1:00 pm - 3:00 pm

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Apr 6th, 1:00 PM Apr 6th, 3:00 PM

Evaluation of a Biological Glucose Concentration-sengings iGEM Part

Upper Atrium/Hallway

In the bodies of people with type one diabetes, the body has lost the ability recognize and respond to glucose concentration in the blood. This leads to an accumulation of glucose is the blood stream. High blood glucose concentrations damage the body in many ways. One theoretical solution to these issues would be to use microbes to replace both of these functions. The ability to recognize glucose concentration is the first part that needs to be developed. Once a part can successfully recognize different glucose concentrations, it can be used in coordination with other parts. Contained in the iGEM registry is such a glucose-concentration sensing part. However, the concentration needed for its activation is unknown. This specific concentration should be discovered, and mutants of the part that respond to different concentrations of glucose should be produced.