Title

Drugs Associated with Fatal Cutaneous Reactions: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Presenter Information

Thomas McKinnon

Department

Biological Sciences

Major

Electrical Engineering

Research Advisor

Stanley, R. Joe

Advisor's Department

Electrical and Computer Engineering

Funding Source

Missouri S&T Opportunities for Undergraduate Research Experiences (OURE) Fellows Program; DERMVIS Research Group

Abstract

Drug reactions account for at least 7% of all hospital admissions worldwide. With insufficient records being submitted by physicians, especially in the US, reactions are not well known. For those records that are submitted to the FDA, the current drug reactions database Adverse Events Reporting System (AERS), MedWatch, is very hard to access by physicians. Writing a PERL code to convert AERS data text files into an Access Database will allow for records to be trended at a much greater rate, along with the printing of html outputs for selected drugs and criteria. For four selected drugs, 47.78% of the records were missing at least one piece of information, leading to an inability to trend the data due to lack of information. This is a common theme that goes along with the lack of access for US physicians to understand drug reactions.

Biography

Thomas McKinnon is a senior at Missouri S&T majoring in Electrical Engineering with a minor in Psychology. This is McKinnon’s second year working the DERMVIS group, as he participated in OURE Research during the 2008-2009 school year working on the Automatic Detection of Blue Gray Ovoids In Skin Lesion Images. Along with working with the DERMVIS, McKinnon is active on campus as a student-assistant for the Miner’s Men’s Basketball Team, founding president of the American Indian Science and Engineering Society, and the INROADS Ambassador on Campus. McKinnon will graduate in May, 2010, and has accepted a job with Sprint/Nextel, whom he has completed four internships with, in Maitland, FL as a Network Engineer.

Research Category

Engineering

Presentation Type

Oral Presentation

Document Type

Presentation

Location

Gasconade Room

Presentation Date

07 Apr 2010, 10:30 am - 11:00 am

Comments

Joint project with John Krumme

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Apr 7th, 10:30 AM Apr 7th, 11:00 AM

Drugs Associated with Fatal Cutaneous Reactions: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Gasconade Room

Drug reactions account for at least 7% of all hospital admissions worldwide. With insufficient records being submitted by physicians, especially in the US, reactions are not well known. For those records that are submitted to the FDA, the current drug reactions database Adverse Events Reporting System (AERS), MedWatch, is very hard to access by physicians. Writing a PERL code to convert AERS data text files into an Access Database will allow for records to be trended at a much greater rate, along with the printing of html outputs for selected drugs and criteria. For four selected drugs, 47.78% of the records were missing at least one piece of information, leading to an inability to trend the data due to lack of information. This is a common theme that goes along with the lack of access for US physicians to understand drug reactions.