Location
Innovation Lab Atrium
Start Date
4-2-2025 2:00 PM
End Date
4-2-2025 3:30 PM
Presentation Date
2 April 2025, 2:00pm - 3:30pm
Biography
Megan Percy is a senior pursuing a Bachelor of Science degree in Chemistry with a minor in Biomedical Engineering. She is treasurer of the Schrenk Hall Chapter of the American Chemical Society at Missouri S&T. In her free time, Megan enjoys reading, trying new restaurants, and spending time with friends and family. This is her last anticipated semester at Missouri S&T, and after graduation she plans to enter the biochemical industry in her hometown of St. Louis, Missouri.
Meeting Name
2025 - Miners Solving for Tomorrow Research Conference
Department(s)
Biological Sciences
Document Type
Poster
Document Version
Final Version
File Type
event
Language(s)
English
Rights
© 2025 The Authors, All rights reserved
Included in
Biochemistry, Biophysics, and Structural Biology Commons, Cell and Developmental Biology Commons
Discovering Localization of FUN19 ORF in Yeast
Innovation Lab Atrium
Comments
Advisor: Katie Shannon
Abstract:
Saccharomyces cerevisiae (S. cerevisiae) has often been used as a tried-and-true model organism in eukaryotic genetic research. Its genome has been fully sequenced, and it is estimated that up to 30% of genes involved in human diseases have orthologs in S. cerevisiae. Therefore, characterizing aspects of its genes and the proteins they code for is important for developing and furthering genetic research. The FUN19 gene has a completely unknown Gene Ontology (GO) but is suspected to function in DNA binding during transcription. As a result of these predictions, it is estimated to produce a protein that is localized in the nucleus. In this study, researchers will confirm the predicted localization by editing the genome of the organism, tagging the C-terminus of the FUN19 gene with a green fluorescent protein (GFP) tag to be viewed under a microscope. This confirmation could provide further evidence of the other suspected GO components.