Location
Innovation Lab Atrium
Start Date
4-3-2025 2:00 PM
End Date
4-3-2025 3:30 PM
Presentation Date
3 April 2025, 2:00pm - 3:30pm
Biography
Amitav Sen is a second-year PhD candidate in Chemistry at Missouri S&T. He received his B.Sc. and M.Sc. degrees in Applied Chemistry and Chemical Engineering (ACCE) from the University of Chittagong, Bangladesh. In 2022, he was awarded the National Science and Technology (NST) Fellowship for his Master’s research on the green synthesis of zinc-oxide nanoparticles (ZnONPs) and its biomedical applications He is currently a Graduate Research Assistant (GRA) in the Department of Chemistry, conducting research under the guidance of Dr. Manashi Nath and Graduate Teaching Assistant (GTA) for GEN-CHEM. His research centers on the development of electrocatalysts of noble composite nanomaterials of transition metals for sensor applications, particularly the development of nonenzymatic biosensors for neurotransmitter detection. His work aims to address challenges in neurological disease diagnostics by designing and synthesizing stable, highly sensitive nanomaterial-based biosensors for real-time neurochemical monitoring.
Meeting Name
2025 - Miners Solving for Tomorrow Research Conference
Department(s)
Electrical and Computer Engineering
Document Type
Poster
Document Version
Final Version
File Type
event
Language(s)
English
Rights
© 2025 The Authors, All rights reserved
Included in
Transition Metal Nanocomposites: Nonenzymatic Biosensor for Neurochemical Detection
Innovation Lab Atrium
Comments
Advisor: Minashi Nath
Abstract:
The advancement of nonenzymatic biosensors for neurotransmitters detection have attracted considerable interest because of their capability for real-time neurochemical monitoring. A hydrothermally synthesized copper telluride (Cu₂Te) nanostructure was created as a highly effective electrocatalyst for detecting norepinephrine (NE). Structural and compositional investigations employing XRD, XPS, and HR-SEM validated the effective synthesis of Cu₂Te. Electrochemical analysis revealed outstanding catalytic activity, with a sensitivity of around 40 μA cm⁻²μM⁻¹, an extensive linear detection range (5–200 nM), and a minimal detection limit 1.98nM at an applied potential of 0.23V relative to Ag|AgCl. The Cu₂Te-modified electrode exhibited enhanced selectivity, stability, and minimal interference from coexisting biomolecules, as demonstrated by voltammetric (CV, DPV, SWV) and amperometric techniques. DPV enabled the simultaneous detection of norepinephrine, uric acid, and serotonin, with distinctively resolved oxidation peaks. We present a highly stable sensor for noninvasive neurochemical monitoring, successfully detecting NE in human tear samples and norepinephrine hydrochloride injections.