Location
Innovation Lab Atrium
Start Date
4-3-2025 10:00 AM
End Date
4-3-2025 11:30 AM
Presentation Date
3 April 2025, 10:00am - 11:30am
Biography
Julia McIntyre is a Biological Sciences Master’s student at Missouri S&T, where she previously earned her BS in Psychology and minor in Biological Sciences. Julia works in the Regenerative Medicine Lab, where her research focuses primarily on changes in mesenchymal stem cells in aging and acute diseases, such as traumatic brain injury. This research has the end goal of better understanding age impact on pathology of acute diseases to improve treatment outcomes for patients.
Meeting Name
2025 - Miners Solving for Tomorrow Research Conference
Department(s)
Biological Sciences
Document Type
Poster
Document Version
Final Version
File Type
event
Language(s)
English
Rights
© 2025 The Authors, All rights reserved
Included in
Video Tracking as an Effective High Throughput Method for mTBI Detection
Innovation Lab Atrium
Comments
Advisor: Julie A. Semon
Abstract:
Due to ambiguous symptoms, mTBI often goes undetected, creating concern for military personnel, who largely suffer from low intensity blast induced mTBI during basic training. Similarly, it is difficult to evaluate clinical symptoms in murine models of mTBI. The Missouri S&T open-field blast model exposed mice to a single blast simulating those frequently experienced by military personnel. Clinical symptoms were evaluated using a traditional behavioral test. Mice were also monitored with a high throughput video tracking. Compared to behavior tests, video tracking was immune to investigator bias, was able to detect clinical symptoms of mTBI at a higher rate, was more reproducible, and saved time and money. Additionally, this is the first study to investigate and detect variations in mTBI effects across different age and sex cohorts. Our video tracking method effectively detects clinical symptoms of neurotrauma, including the historically challenging mTBI.