Responsive Nanoassemblies Via Interpolyelectrolyte Complexation of Amphiphilic Block Copolymer Micelles
Shell "locked" nanoassemblies ranging in size from 34 to 78 nm have been prepared from interpolyelectrolyte complexation of block copolymer micelles of poly[(N,N-dimethylacrylamide)-b-(N-acryloylalanine)-b-(N- isopropylacrylamide)] with the homopolymer poly(ar-vinylbenzyl)trimethylammonium chloride above the unimer to micelle phase transition temperature of the block copolymer in water. Of technological significance is the reversibility of the shell cross-linking by addition of 0.4 M NaCl, allowing micelle dissociation below the lower critical solution temperature of the copolymer micelles. Poly(N-acryloylalanine) (AAL) and block copolymers were prepared directly in water via controlled reversible addition fragmentation chain transfer (RAFT) polymerization utilizing mono- and difunctional poly(N,N-dimethylacrylamide) macroCTAs.
B. S. Lokitz et al., "Responsive Nanoassemblies Via Interpolyelectrolyte Complexation of Amphiphilic Block Copolymer Micelles," Macromolecules, vol. 39, no. 25, pp. 8594 - 8602, American Chemical Society (ACS), Dec 2006.
The definitive version is available at https://doi.org/10.1021/ma061672y
Materials Science and Engineering
Keywords and Phrases
Copolymer micelles; Micelle dissociation; Reversible addition fragmentation chain transfer (RAFT) polymerization, Block copolymers; Complexation; Crosslinking; Dissociation; Micelles; Phase transitions; Polyelectrolytes, Nanostructured materials
International Standard Serial Number (ISSN)
Article - Journal
© 2006 American Chemical Society (ACS), All rights reserved.
01 Dec 2006