"The purpose of this investigation was to develop a samarium containing aluminosilicate glass with properties suitable for use in the treatment of rheumatoid arthritis. Microspheres made from these compositions would be neutron activated to produce radioactive Sm-153 which has beta-particle energies suitable for treating rheumatoid arthritis as well as appropriate gamma-ray emission for nuclear imaging. The properties of Sm2O3 · AI2O3 · SiO2 glasses containing 10 to 25 mole% Sm2O3 were evaluated as a function of composition. The density, refractive index, thermal expansion coefficient, and microhardness increased with increasing Sm2O3 content. The dissolution rate in 1N HCl and deionized water at 37°C increased whereas the dissolution rate in deionized water at 70°C decreased with increasing Sm2O3 content. Several glasses had excellent properties suitable for radiotherapeutic applications. The composition range for the glasses best suited for these applications was (10-25) Sm2O3 · (20-35) Al2O3 · (40-70) SiO2 (mole%)"--Abstract, page iii.
Day, D. E.
Moore, Robert E., 1930-2003
Brown, Roger F.
Materials Science and Engineering
M.S. in Ceramic Engineering
University of Missouri--Rolla
ix, 59 pages
© 1988 Erik Michael Erbe, All rights reserved.
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Erbe, Erik M., "Glass formation and properties in the Sm₂O₃·Al₂O₃·SiO₂ system" (1988). Masters Theses. 645.
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