Masters Theses

Author

Erik M. Erbe

Abstract

"The purpose of this investigation was to develop a samarium containing aluminosilicate glass with properties suitable for use in the treatment of rheumatoid arthritis. Microspheres made from these compositions would be neutron activated to produce radioactive Sm-153 which has beta-particle energies suitable for treating rheumatoid arthritis as well as appropriate gamma-ray emission for nuclear imaging. The properties of Sm2O3 · AI2O3 · SiO2 glasses containing 10 to 25 mole% Sm2O3 were evaluated as a function of composition. The density, refractive index, thermal expansion coefficient, and microhardness increased with increasing Sm2O3 content. The dissolution rate in 1N HCl and deionized water at 37°C increased whereas the dissolution rate in deionized water at 70°C decreased with increasing Sm2O3 content. Several glasses had excellent properties suitable for radiotherapeutic applications. The composition range for the glasses best suited for these applications was (10-25) Sm2O3 · (20-35) Al2O3 · (40-70) SiO2 (mole%)"--Abstract, page iii.

Advisor(s)

Day, D. E.

Committee Member(s)

Moore, Robert E., 1930-2003
Brown, Roger F.

Department(s)

Materials Science and Engineering

Degree Name

M.S. in Ceramic Engineering

Publisher

University of Missouri--Rolla

Publication Date

Fall 1988

Pagination

ix, 59 pages

Note about bibliography

Includes bibliographic references (pages 23-25).

Rights

© 1988 Erik Michael Erbe, All rights reserved.

Document Type

Thesis - Restricted Access

File Type

text

Language

English

Thesis Number

T 5755

Print OCLC #

19452884

Electronic OCLC #

1090547557

Link to Catalog Record

Electronic access to the full-text of this document is restricted to Missouri S&T users. Otherwise, request this publication directly from Missouri S&T Library or contact your local library.

http://laurel.lso.missouri.edu/record=b2138598~S5

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