"A survey of the ability of basidiomycetes to convert tryptophan, tryptamine and indole acetic acid to other acidic indoles has been made.
The product formed from tryptamine by Tricholoma nudum was identified as indole acetic acid. The product formed by Cantharellus cibarius from D-tryptophan was identified as N-acetyl-D-tryptophan. The products were purified and identified by means of paper chromatography, thin layer chromatography, infrared spectroscopy and melting points.
The conversion of tryptamine and D-tryptophan was also studied in cultures of Leucopaxillus paradoxus, Hygrophorus conicus and Naucoria confragosa. H. conicus, L. paradoxus and N. confragosa transformed tryptamine and indole acetic acid into oxindole acetic acid. L. paradoxus and N. confragosa also transformed D-tryptophan to oxindole acetic acid, but in poor yield. Two unidentified indole compounds were found in the culture media of L. paradoxus and N. confragosa grown on tryptamine.
Another product formed from tryptamine and indole acetic acid by T. nudum and N. confragosa was identified as 5-hydroxyindole acetic acid. T. nudum also transformed N,N-dimethyl-tryptamine into indole acetic acid and 5-hydroxy-indole acetic acid, but no transformation was observed with either α -ethyl- or α -methyl-tryptamine
An attempt to develop an assay method for the mono-amine oxidase of T. nudum was not notably successful"--Abstract, page i.
Siehr, Donald J.
Conrad, Frank H., 1902-1983
Wixson, Bobby G.
Hanna, Samir B.
M.S. in Chemistry
University of Missouri at Rolla
iv, 60 pages
© 1967 Chung-Ke Chang, All rights reserved.
Thesis - Open Access
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Chang, Chung-Ke, "The acidic transformaion products of indoles formed by basidiomycetes" (1967). Masters Theses. 2930.