Large-scale gene expression data coming from microarray experiments provide us a new means to reveal fundamental cellular processes, investigate functions of genes, and understand relations and interactions among them. To infer genetic regulatory networks from these data with effective computational tools has become increasingly important Several mathematical models, including Boolean networks, Bayesian networks, dynamic Bayesian networks, and linear additive regulation models, have been used to explore the behaviors of regulatory networks. In this paper, we investigate the inference of genetic regulatory networks from time series gene expression in the framework of recurrent neural network model.

Meeting Name

26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2004


Electrical and Computer Engineering

Second Department

Computer Science

Keywords and Phrases

Backpropagation; Biochemistry; Biology Computing; Cellular Biophysics; Fundamental Cellular Process; Gene Function; Gene Interactions; Gene Relations; Genetic Regulatory Networks; Genetics; Molecular Biophysics; Recurrent Neural Nets; Recurrent Neural Network Models; Time Series; Time Series Gene Expression

Document Type

Article - Conference proceedings

Document Version

Final Version

File Type





© 2004 Institute of Electrical and Electronics Engineers (IEEE), All rights reserved.

Publication Date

01 Jan 2004