Cu2Se, synthesized through one-pot hydrothermal synthesis, was identified as highly efficient bifunctional sensor for co-detection of glucose and dopamine with high selectivity. As-synthesized copper selenide could electro-oxidize glucose and dopamine at different applied potentials. Glucose oxidation was observed at 0.35 V while dopamine oxidized at 0.2 V. This copper selenide-based non-enzymatic sensor showed high sensitivity for both glucose (15.341 mA mM-1 cm-2) and dopamine (12.43 μA μM-1 cm-2) with low limit of detection (0.26 μM and 84 nM). Such high sensitivity and low LOD makes this sensor attractive for possible detection of glucose/dopamine in physiological body fluids which have low concentration of these biomolecules. Extremely low applied potential for detection also makes it ideal for integrating into wearable continuous monitoring devices with low operational power requirement. This sensor showed high reproducibility, reusability and long-term operational stability along with high degree of selectivity for dopamine and glucose sensing in presence of other interferents. Graphic abstract: [Figure not available: see fulltext.].
H. Singh et al., "Copper Selenide as Multifunctional Non-Enzymatic Glucose and Dopamine Sensor," Journal of Materials Research, Cambridge University Press, May 2021.
The definitive version is available at https://doi.org/10.1557/s43578-021-00227-0
Keywords and Phrases
Dopamine; Glucose; Selectivity And Stability; Sensitivity
International Standard Serial Number (ISSN)
Article - Journal
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11 May 2021