Abstract

A pH micro-probe, a temperature micro-probe, and an immuno-based micro-probe each include a shaft for transmuting an input light signal and a tip for inserting into a cell or other substance for measuring pH, temperature, and/or antigens. The pH micro-probe and the temperature micro-probe each include a luminescent material positioned on the tip of the micro-probe. The light signal excites the luminescent material so that the luminescent material emits a luminescent light signal. The luminescent light signal has a property value dependent on the pH or temperature being measured and reflects back through the shaft for being measured by a light signal measuring device. The immuno-based micro-probe includes a reflective material that has an effective refractive index dependent on the number of antigen-antibody bonds present on the reflective material.

Department(s)

Chemistry

Second Department

Electrical and Computer Engineering

Comments

The research for the microprobe began with an award from the National Institutes of Health in 2012 to develop a multifunctional single-cell analyzer (grant number1R21GM104696-01).

12 Apr 2018: Publication of US20180100806A1

Patent Application Number

US15/837,597

Patent Number

US10591418B2

Document Type

Patent

Document Version

Final Version

File Type

text

Language(s)

English

Rights

© 2020 Curators of the University of Missouri and Clemson University, All rights reserved.

Publication Date

17 Mar 2020

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