Metal-Ion Responsive Reversible Assembly of DNA Origami Dimers: G-Quadruplex Induced Intermolecular Interaction
We present a novel metal-ion stimulated organization of DNA origami nanostructures by employing G-quadruplexes as stimuli-responsive bridges. The reversible assembly process of DNA origami was the result of conformational changes between the G-quadruplex and its single-strand state induced by monovalent cations. This study might stimulate a new design of responsive DNA-based intelligent nanomaterials.
S. Yang et al., "Metal-Ion Responsive Reversible Assembly of DNA Origami Dimers: G-Quadruplex Induced Intermolecular Interaction," Nanoscale, vol. 10, no. 8, pp. 3626-3630, Royal Society of Chemistry, Feb 2018.
The definitive version is available at https://doi.org/10.1039/c7nr09458b
Mechanical and Aerospace Engineering
Keywords and Phrases
Assembly process; Conformational change; DNA origamis; G-quadruplexes; Intermolecular interactions; Monovalent cations; Stimuli-responsiv
International Standard Serial Number (ISSN)
Article - Journal
© 2018 Royal Society of Chemistry, All rights reserved.
01 Feb 2018